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American Cruise Lines

American Serenade



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Detailed Ship Information: Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard... Read More

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7 Night - Lower Mississippi River Cruise from New Orleans, LA to Memphis, TN
Starting in New Orleans, LA; with stops in Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Memphis, TN

7 Night - Lower Mississippi River Cruise from Memphis, TN to New Orleans, LA
Starting in Memphis TN; with stops in Vicksburg, MS; Natchez, MS; St. Francisville, LA; Baton Rouge, LA; Houmas House, LA; New Orleans, LA

7 Night - Music Cities Cruise from Memphis, TN to Nashville, TN
Starting in Memphis TN; Cruising the Mississippi and Ohio River; with stops in Paducah, KY; Cruising Lake Barkley and the Cumberland River; Dover, TN; Clarksville, TN; Nashville, TN
2023 Sails: May 25, 2024: Oct 16

7 Night - The Tennessee Rivers Cruise from Nashville, TN to Chattanooga, TN
Starting in Nashville, TN; with stops in Clarksville, TN; Paducah, KY; Savannah, TN; Florence, AL; Decatur, AL; Chattanooga, TN

7 Night - Music Cities Cruise from Nashville, TN to Memphis, TN
Starting in Nashville, TN; with stops in Clarksville, TN; Dover, TN; Cruising Lake Barkley and the Cumberland River; Paducah, KY; Cruising the Mississippi and Ohio River; Memphis TN
2023 Sails: Jul 27, 2024: Nov 6

7 Night - Upper Mississippi River Cruise from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; Alton, IL; St. Louis, MO
2023 Sails: Aug 31, Sep 14, Sep 28, 2024: Jul 10, Jul 24, Aug 7, Aug 21, Sep 4

7 Night - Upper Mississippi River Cruise from St. Louis, MO to St. Paul, MN
Starting in St. Louis, MO; with stops in Alton, IL; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2023 Sails: Sep 7, Sep 21, Oct 5, 2024: Jul 17, Jul 31, Aug 14, Aug 28, Sep 11

7 Night - New Orleans - New Orleans
Starting in New Orleans, LA; with stops in Oak Alley, LA; Natchez, MS; Vicksburg, MS; St. Francisville, LA; Baton Rouge, LA; Houmas House, LA; New Orleans, LA
2024 Sails: Oct 2, Nov 20, Nov 26, Dec 2, Dec 8

14 Night - Grand Heartland Cruise from St. Paul, MN to New Orleans, LA
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 12, 2024: Sep 18

21 Night - Complete Mississippi River Cruise from New Orleans, LA to St. Paul, MN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2023 Sails: Aug 10, 2024: Jun 19

About American Serenade

Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.

American Serenade also showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms offer full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. The new ship also features an on board fitness center and many spacious lounges where you can relax after the day's adventures.


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