Niagara Falls Cruise Departures

Cruises that depart from North America: Canada: Ontario: Niagara Falls

Cruises that visit Niagara Falls

Click on a cruise ship itinerary sailing from Niagara Falls (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Niagara Falls), please visit: Cruise Search or try our Virtual Cruise Advisor™.

8 Night - Port Colborne to Milwaukee
Starting in Niagara Falls (Port Colborne), ON; with stops in Clevelend, OH; Scenic Great Lakes Cruising; Little Current/Manitoulin Island, ON; Sault Ste. Marie (Soo Locks), MI; Mackinac Island, MI; Scenic Great Lakes Cruising; Chicago/Milwaukee, WI
2024 Sails: May 30, Jun 13, Sep 7, More...

American Queen Voyages, Ocean Voyager

8 Night - Port Colborne to Milwaukee
Starting in Niagara Falls (Port Colborne), ON; with stops in Cleveland, OH; Little Current/Manitoulin Island, ON; Sault Ste. Marie (Soo Locks), MI; Mackinac Island, MI; Chicago/Milwaukee, WI
2024 Sails: Jul 19, Aug 30, More...

Niagara Falls Cruise Departures