Minneapolis River Cruise Departures

River Cruises that depart from North America: United States: Minnesota: Minneapolis

River Cruises that visit Minneapolis

See all Cruises that depart from Minneapolis

Mississippi River Cruises

Click on a cruise ship itinerary sailing from Minneapolis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Minneapolis), please visit: Cruise Search or try our Virtual Cruise Advisor™.

8 Night - Minneapolis to St. Louis
Starting in Minneapolis, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis (Alton)
2023 Sails: Jul 10, Jul 24, 2024: Aug 24, More...

American Queen Voyages, American Queen

American Queen Voyages, American Countess

22 Night - Minneapolis to Pittsburgh
Starting in Minneapolis (Red Wing), MN; with stops in Red Wing, MN; Minneapolis, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Chester, IL; Cape Girardeau, MO; Paducah, KY; Henderson, KY; Owensboro, KY; Brandenburg, KY; Louisville, KY; Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Wheeling, WV; Pittsburgh, PA
2023 Sails: Jul 24, More...

American Queen Voyages, American Queen

15 Night - Minneapolis to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; Kimmswick, MO; Memphis, TN; Cleveland, MS; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2023 Sails: Aug 6, Oct 1, 2024: Aug 11, More...

American Queen Voyages, American Countess

15 Night - Minneapolis to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Cleveland, MS; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2023 Sails: Sep 4, 2024: Oct 5, More...

American Queen Voyages, American Duchess

15 Night - Minneapolis to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Cleveland, MS; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2024 Sails: Jul 22, More...

Minneapolis River Cruise Departures