St Louis River Cruises
River Cruises that visit North America: United States: Missouri: St Louis
River Cruises that depart from St Louis
See all Cruises that visit St Louis
Mississippi River Cruises
River cruises by river name
River Cruises that visit North America: United States: Missouri: St Louis
River Cruises that depart from St Louis
See all Cruises that visit St Louis
Mississippi River Cruises
Click on a cruise ship itinerary that visits St Louis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just St Louis), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
8 Night - American Culinary Experience Cruise from St. Louis to Louisville
Starting in St. Louis, MO; with stops in Chester, IL; Cape Girardeau, MO; Paducah, KY; Henderson, KY; Owensboro, KY; Brandenburg, KY; Louisville, KY
2023 Sails: Jul 31, More...
Starting in St. Louis, MO; with stops in Chester, IL; Cape Girardeau, MO; Paducah, KY; Henderson, KY; Owensboro, KY; Brandenburg, KY; Louisville, KY
2023 Sails: Jul 31, More...
21 Night - Complete Mississippi River Cruise from New Orleans, LA to St. Paul, MN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2023 Sails: Aug 10, 2024: Jun 19, More...
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2023 Sails: Aug 10, 2024: Jun 19, More...
22 Night - Pittsburgh to Minneapolis
Starting in Pittsburgh, PA; with stops in Wheeling, WV; Marietta, OH; Huntington, WV; Augusta, KY; Cincinnati, OH; Madison, IN; Louisville, KY; Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO; St. Louis (Alton), MO; Hannibal, MO; Bettendorf, IA; Dubuque, IA; La Crosse, WI; Red Wing, MN; Minneapolis (Red Wing), MN
2023 Sails: Aug 14, More...
Starting in Pittsburgh, PA; with stops in Wheeling, WV; Marietta, OH; Huntington, WV; Augusta, KY; Cincinnati, OH; Madison, IN; Louisville, KY; Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO; St. Louis (Alton), MO; Hannibal, MO; Bettendorf, IA; Dubuque, IA; La Crosse, WI; Red Wing, MN; Minneapolis (Red Wing), MN
2023 Sails: Aug 14, More...
8 Night - Louisville to St. Louis
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2023 Sails: Aug 21, 2024: Jul 13, More...
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2023 Sails: Aug 21, 2024: Jul 13, More...
8 Night - Burbon: An American Spirit Cruise from Louisville to St. Louis
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2023 Sails: Aug 21, More...
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO (Alton)
2023 Sails: Aug 21, More...
15 Night - Minneapolis to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Cleveland, MS; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2023 Sails: Sep 4, 2024: Oct 5, More...
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Cleveland, MS; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2023 Sails: Sep 4, 2024: Oct 5, More...
14 Night - Grand Heartland Cruise from St. Paul, MN to New Orleans, LA
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 7, More...
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 7, More...
14 Night - Grand Heartland Cruise from St. Paul, MN to New Orleans, LA
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 12, 2024: Sep 18, More...
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 12, 2024: Sep 18, More...
14 Night - Grand Heartland Cruise from St. Paul, MN to New Orleans, LA
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 26, Nov 3, 2024: Oct 5, More...
Starting in St. Paul, MN; with stops in Winona, MN; Dubuque, IA; Davenport, IA; Fort Madison, IA; Hannibal, MO; St. Louis, MO; Day of River Cruising; Memphis, TN; Greenville, MS; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2023 Sails: Oct 26, Nov 3, 2024: Oct 5, More...
21 Night - Complete Mississippi River Cruise from New Orleans, LA to St. Paul, MN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2024 Sails: Jun 1, Aug 17, More...
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2024 Sails: Jun 1, Aug 17, More...