Compare offers from multiple travel agencies

Find your cruise
& request quotes

Compare members only prices,
upgrades, cabin credits & more!

Contact your preferred agent
for questions or to book your cruise

Over 1 million members

Santo Domingo Cruise Departures

Cruises that depart from Caribbean: Dominican Republic: Santo Domingo

Cruises that visit Santo Domingo

Click on a cruise ship itinerary sailing from Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Caribbean
Shore Excursions

Costa Cruise Lines, Costa Pacifica

7 Night - Caribbean from Santo Domingo
Starting in Santo Domingo with stops in Ocho Rios, Grand Turk, Amber Cove, Samana, Catalina Island
2023 Sails: Dec 22, More...

Costa Cruise Lines, Costa Pacifica

9 Night - Caribbean from Santo Domingo
Starting in Santo Domingo with stops in St. Lucia, Barbados, Guadeloupe, Dominica, Antigua, St. Maarten, Tortola, La Romana
2023 Sails: Dec 29, More...

Santo Domingo Cruise Departures

Connecting cruisers with the best cruise prices on discount cruises since 2003. Privacy Policy

Let our Virtual Cruise Advisor(TM) recommend the best cruises for you.