Phnom Penh Cruise Departures

Cruises that depart from Asia/Far East: Cambodia: Phnom Penh

Cruises that visit Phnom Penh

See all River Cruises that depart from Phnom Penh

Click on a cruise ship itinerary sailing from Phnom Penh (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Phnom Penh), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Avalon Waterways, Avalon Saigon

7 Night - Mekong Discovery (Southbound) (WSH) - Saigon
Starting in Phnom Penh with stops in Angkor Ban, Chau Doc, Cu Lao Gieng, Vinh Long, Ho Chi Minh City
2023 Sails: Feb 16, Mar 2, Mar 16, Mar 30, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12, Oct 26, Nov 9, Nov 23, Dec 7, More...

Emerald Cruises, Emerald Harmony

8 Night - Majestic Mekong River Cruise: Phnom Penh to Ho Chi Minh City aboard Emerald Harmony (Cruise)
Starting in Phnom Penh with stops in Vietnam / Cambodia Border Crossing, Long Khanh Island, My An Hung, Cai Be, Ho Chi Minh City
2023 Sails: Aug 19, Sep 2, Sep 16, Sep 30, Oct 14, Nov 11, Nov 25, Dec 9, Dec 23, 2024: Jan 6, Jan 20, Feb 3, Feb 17, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, More...

Avalon Waterways, Avalon Saigon

7 Night - Mekong Discovery (Southbound) (WSH) - Saigon
Starting in Phnom Penh with stops in Angkor Ban, Chau Doc, Cu Lao Gieng, Vinh Long, Ho Chi Minh City
2024 Sails: Jan 18, Feb 1, Feb 15, Feb 29, Mar 14, Mar 28, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, More...

Emerald Cruises, Emerald Harmony

8 Night - Majestic Mekong River Cruise: Phnom Penh to Ho Chi Minh City aboard Emerald Harmony (Cruise)
Starting in Phnom Penh with stops in Vietnam / Cambodia Border Crossing, Long Khanh Island, My An Hung, Cai Be, Ho Chi Minh City
2024 Sails: Aug 3, Aug 17, Aug 31, Sep 14, Sep 28, Oct 12, Oct 26, Nov 9, Nov 23, Dec 7, Dec 21, 2025: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, May 10, More...

Phnom Penh Cruise Departures