South Carolina Cruises

Cruises that visit North America: United States: South Carolina

Cruises that depart from South Carolina

See all River Cruises that visit South Carolina

Click on a cruise ship itinerary that visits South Carolina (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Carolina), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Holland America Line (HAL), HAL Nieuw Amsterdam

14 Night - Western / Southern Caribbean
Starting in Fort Lauderdale with stops in Georgetown, Falmouth, Grand Turk, Half Moon Cay, Willemstad
2023 Sails: Feb 5, More...

Holland America Line (HAL), HAL Nieuw Amsterdam

7 Night - Western Caribbean
Starting in Fort Lauderdale with stops in Georgetown, Falmouth, Grand Turk, Half Moon Cay
2023 Sails: Feb 5, More...

Holland America Line (HAL), HAL Nieuw Statendam

14 Night - Tropical / Western Caribbean
Starting in Fort Lauderdale with stops in Nassau, Amber Cove, Grand Turk, Half Moon Cay, Georgetown, Ocho Rios
2023 Sails: Feb 11, More...

American Cruise Lines, American Independence

7 Night - Historic South and Golden Isles Cruise from Charleston, SC to Jacksonville, FL
Starting in Charleston, SC; with stops in Beaufort, SC; Hilton Head Island, SC; Savannah, GA; Cruising the Intercoastal Waterway; Jekyll Island, GA; St. Simons Island, GA; Amelia Island, FL; Jacksonville, FL
2023 Sails: Feb 18, Mar 4, Mar 18, Apr 1, Apr 15, Nov 25, Dec 9, Dec 28, 2024: Feb 17, Mar 2, Mar 16, Mar 30, Apr 13, Nov 27, Dec 11, Dec 31, More...

Holland America Line (HAL), HAL Nieuw Statendam

7 Night - Western Caribbean
Starting in Fort Lauderdale with stops in Half Moon Cay, Georgetown, Ocho Rios, Nassau
2023 Sails: Feb 18, More...

Holland America Line (HAL), HAL Nieuw Statendam

14 Night - Western / Southern Caribbean
Starting in Fort Lauderdale with stops in Half Moon Cay, Georgetown, Ocho Rios, Nassau, Oranjestad, Willemstad
2023 Sails: Feb 18, More...

Royal Caribbean International (RCL), RCL Enchantment of the Seas

8 Night - Southeast Coast & Bahamas Cruise
Starting in Baltimore with stops in Charleston, Port Canaveral, Nassau, Grand Bahama Island
2023 Sails: Feb 23, Mar 23, More...

American Cruise Lines, American Independence

7 Night - Historic South and Golden Isles Cruise from Jacksonville, FL to Charleston, SC
Starting in Jacksonville, FL; with stops in Amelia Island, FL; Jekyll Island, GA; St. Simons Island, GA; Cruising the Intercoastal Waterway; Savannah, GA; Hilton Head Island, SC; Beaufort, SC; Charleston, SC
2023 Sails: Feb 25, Mar 11, Mar 25, Apr 8, Nov 18, Dec 2, Dec 20, 2024: Feb 10, Feb 24, Mar 9, Mar 23, Apr 6, Nov 20, Dec 4, Dec 23, More...

Oceania Cruises, Oceania Riviera

20 Night - Sizzling Sunny Array - Miami Florida to Miami Florida
Starting in Miami with stops in Cruising the Atlantic Ocean, Puerto Plata, San Juan, Gustavia, Roseau, Kingstown, Basseterre, Nassau, Royal Naval Dockyard, Charleston, Port Canaveral
2023 Sails: Mar 2, More...

Viking Ocean, Viking Octantis

64 Night - Longitudinal World Cruise I : Buenos Aires to Milwaukee
Starting in Buenos Aires with stops in Ushuaia, Sail the Drake Passage, Explore Antarctica, Cape Horn, Explore Chilean Glaciers, Punta Arenas, Chilean Fjords, Tortel, Castro, Sail the Pacific Ocean, Valparaiso, Iquique, Callao, Manta, Panama Canal, Colon, Sail the Caribbean Sea, Cozumel, Sail the Gulf of Mexico, Fort Lauderdale, Sail the Atlantic Ocean, Charleston, Norfolk, New York, Lunenburg, Louisbourg, Cap-aux-Meules, St. Lawrence River, Quebec City, Trois-Rivieres, St. Lawrence Seaway Locks, Toronto, Welland Canal, Point Pelee, Detroit, Alpena, Mackinac Island, Milwaukee
2023 Sails: Mar 2, More...

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