Florida River Cruise Departures

River Cruises that depart from North America: United States: Florida

River Cruises that visit Florida

See all Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Amelia Island : Jacksonville

American Cruise Lines, American Eagle

7 Night - Historic South and Golden Isles Cruise from Jacksonville, FL to Charleston, SC
Starting in Jacksonville, FL; with stops in Amelia Island, FL; Jekyll Island, GA; St. Simons Island, GA; Cruising the Intercoastal Waterway; Savannah, GA; Hilton Head Island, SC; Beaufort, SC; Charleston, SC
2023 Sails: Nov 3, Nov 17, Dec 1, Dec 15, Dec 29, 2024: Mar 11, Mar 25, Apr 8, Apr 22, May 6, Dec 8, Dec 22, More...

American Cruise Lines, American Eagle

7 Night - Great Rivers of Florida Cruise Roundtrip from Jacksonville, FL
Starting in Jacksonville, FL; with stops in Green Cove Springs, FL; Palatka, FL; Amelia Island, FL; Cruising the Tolomato River; St. Augustine, FL; Jacksonville, FL
2024 Sails: Feb 5, Feb 12, Feb 19, Feb 26, Mar 4, Nov 24, Dec 1, More...

American Cruise Lines, American Eagle

14 Night - East Coast Inland Passage Cruise from Jacksonville, FL to Baltimore, MD
Starting in Jacksonville, FL / Amelia Island, FL; with stops in Fernandina Beach, FL; Jekyll Island, GA; St. Simons Island, GA; Savannah, GA; Hilton Head, SC; Beaufort, SC; Charleston, SC; Wilmington, NC; Beaufort, NC / Morehead City, NC; Kitty Hawk, NC; Norfolk, VA; St. Michaels, MD; Baltimore, MD
2024 Sails: May 20, More...

Florida River Cruise Departures