Madrid Cruise Departures
Cruises that depart from Europe: Spain: Madrid
Cruises that visit Madrid
See all River Cruises that depart from Madrid
Cruises that depart from Europe: Spain: Madrid
Cruises that visit Madrid
See all River Cruises that depart from Madrid
Click on a cruise ship itinerary sailing from Madrid (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Madrid), please visit: Cruise Search or try our Virtual Cruise Advisor™.
13 Night - Flavors of Portugal & Spain : Madrid to Lisbon : 7-Night Cruise with 3 Nights Pre-Cruise and 3 Nights Post-Cruise : ms AmaVida
Starting in Madrid with stops in Toledo, Vega Terron, Pinhao, Regua, Entre-os-Rios, Porto, Lisbon, Sintra
2023 Sails: Apr 1, Apr 15, Apr 29, May 13, May 27, Jun 10, Jul 8, Jul 22, Aug 5, Aug 19, Sep 16, Sep 30, Oct 14, Oct 28, More...
Starting in Madrid with stops in Toledo, Vega Terron, Pinhao, Regua, Entre-os-Rios, Porto, Lisbon, Sintra
2023 Sails: Apr 1, Apr 15, Apr 29, May 13, May 27, Jun 10, Jul 8, Jul 22, Aug 5, Aug 19, Sep 16, Sep 30, Oct 14, Oct 28, More...
13 Night - Highlights of Spain - Tour 2A from Madrid, Spain to Rome (Civitavecchia), Italy
Land first (6 days), followed by cruise (7 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 4 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy
2023 Sails: Apr 9, Apr 30, May 21, Jun 11, Jul 2, Jul 23, Aug 13, Sep 3, Sep 24, More...
Land first (6 days), followed by cruise (7 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 4 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy
2023 Sails: Apr 9, Apr 30, May 21, Jun 11, Jul 2, Jul 23, Aug 13, Sep 3, Sep 24, More...
20 Night - Highlights of Spain - Tour 2B from Madrid, Spain to Athens (Piraeus), Greece
Land first (6 days), followed by cruise (14 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 10 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Naples, Italy (for Capri & Pompeii); Crete (Heraklion), Greece; Kusadasi, Turkey (for Ephesus); Istanbul, Turkey; Mykonos, Greece; Athens (Piraeus), Greece
2023 Sails: Apr 9, Apr 30, May 21, Jun 11, Jul 2, Jul 23, Aug 13, Sep 3, Sep 24, More...
Land first (6 days), followed by cruise (14 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 10 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Naples, Italy (for Capri & Pompeii); Crete (Heraklion), Greece; Kusadasi, Turkey (for Ephesus); Istanbul, Turkey; Mykonos, Greece; Athens (Piraeus), Greece
2023 Sails: Apr 9, Apr 30, May 21, Jun 11, Jul 2, Jul 23, Aug 13, Sep 3, Sep 24, More...
27 Night - Highlights of Spain - Tour 2C from Madrid, Spain to Barcelona, Spain
Land first (6 days), followed by cruise (21 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 15 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Naples, Italy (for Capri & Pompeii); Crete (Heraklion), Greece; Kusadasi, Turkey (for Ephesus); Istanbul, Turkey; Mykonos, Greece; Athens (Piraeus), Greece; Santorini, Greece; Kotor, Montenegro; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Barcelona, Spain
2023 Sails: Apr 9, Apr 30, May 21, Jun 11, Jul 2, Jul 23, Aug 13, Sep 3, Sep 24, More...
Land first (6 days), followed by cruise (21 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 15 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Naples, Italy (for Capri & Pompeii); Crete (Heraklion), Greece; Kusadasi, Turkey (for Ephesus); Istanbul, Turkey; Mykonos, Greece; Athens (Piraeus), Greece; Santorini, Greece; Kotor, Montenegro; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Barcelona, Spain
2023 Sails: Apr 9, Apr 30, May 21, Jun 11, Jul 2, Jul 23, Aug 13, Sep 3, Sep 24, More...
12 Night - Exploring the Douro, plus Lisbon & Madrid - Westbound Aboard ms Andorinha
Starting in Madrid with stops in Salamanca, Castelo Rodrigo, Pinhao, Peso da Regua, Guimaraes, Porto, Lisbon
2023 Sails: Apr 19, May 31, Jul 26, Aug 16, Nov 1, More...
Starting in Madrid with stops in Salamanca, Castelo Rodrigo, Pinhao, Peso da Regua, Guimaraes, Porto, Lisbon
2023 Sails: Apr 19, May 31, Jul 26, Aug 16, Nov 1, More...
10 Night - Madrid & Secrets of the Douro: Madrid to Porto aboard Emerald Radiance (Cruise)
Starting in Madrid with stops in Porto, Pinhao, Vega De Terron, Salamanca, Regua
2023 Sails: May 25, Jul 6, Oct 26, More...
Starting in Madrid with stops in Porto, Pinhao, Vega De Terron, Salamanca, Regua
2023 Sails: May 25, Jul 6, Oct 26, More...
13 Night - Madrid to Lisbon & Secrets of the Douro: Madrid to Lisbon aboard Emerald Radiance (Cruise)
Starting in Madrid with stops in Porto, Pinhao, Vega De Terron, Salamanca, Regua, Lisbon
2023 Sails: May 25, Jul 6, Oct 26, More...
Starting in Madrid with stops in Porto, Pinhao, Vega De Terron, Salamanca, Regua, Lisbon
2023 Sails: May 25, Jul 6, Oct 26, More...
27 Night - 27 Highlights of Spain - Tour 2C from Barcelona, Spain to Barcelona, Spain
3 Land Destinations Madrid, Spain ; Valencia, Spain ; Barcelona, Spain 15 Ports Barcelona, Spain ; Gibraltar ; Marseille (Provence), France ; Genoa, Italy ; Florence/Pisa (Livorno), Italy ; Rome (Civitavecchia), Italy ; Naples, Italy (for Capri & Pompeii) ; Crete (Heraklion), Greece ; Kusadasi, Turkey (for Ephesus) ; Istanbul, Turkey ; Mykonos, Greece ; Athens (Piraeus), Greece ; Santorini, Greece ; Kotor, Montenegro ;Corfu, Greece; Sicily (Messina), Italy ; Barcelona, Spain
2023 Sails: Jul 2, More...
3 Land Destinations Madrid, Spain ; Valencia, Spain ; Barcelona, Spain 15 Ports Barcelona, Spain ; Gibraltar ; Marseille (Provence), France ; Genoa, Italy ; Florence/Pisa (Livorno), Italy ; Rome (Civitavecchia), Italy ; Naples, Italy (for Capri & Pompeii) ; Crete (Heraklion), Greece ; Kusadasi, Turkey (for Ephesus) ; Istanbul, Turkey ; Mykonos, Greece ; Athens (Piraeus), Greece ; Santorini, Greece ; Kotor, Montenegro ;Corfu, Greece; Sicily (Messina), Italy ; Barcelona, Spain
2023 Sails: Jul 2, More...
27 Night - Highlights of Spain - Tour 2C from Madrid, Spain to Barcelona, Spain
Land first (6 days), followed by cruise (21 days)3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain 15 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Naples, Italy (for Capri & Pompeii); Crete (Heraklion), Greece; Kusadasi, Turkey (for Ephesus); Istanbul, Turkey; Mykonos, Greece; Athens (Piraeus), Greece; Santorini, Greece; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Barcelona, Spain
2023 Sails: Jul 2, More...
Land first (6 days), followed by cruise (21 days)3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain 15 Ports: Barcelona, Spain; Gibraltar; Marseille (Provence), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Naples, Italy (for Capri & Pompeii); Crete (Heraklion), Greece; Kusadasi, Turkey (for Ephesus); Istanbul, Turkey; Mykonos, Greece; Athens (Piraeus), Greece; Santorini, Greece; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Barcelona, Spain
2023 Sails: Jul 2, More...
17 Night - Highlights of Spain - Tour 2D from Madrid, Spain to Rome (Civitavecchia), Italy
Land first (6 days), followed by cruise (11 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 7 Ports: Barcelona, Spain; Toulon/Provence (La Seyne), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Rome (Civitavecchia), Italy
2023 Sails: Oct 15, Nov 6, More...
Land first (6 days), followed by cruise (11 days); 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 7 Ports: Barcelona, Spain; Toulon/Provence (La Seyne), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Rome (Civitavecchia), Italy
2023 Sails: Oct 15, Nov 6, More...