St Louis River Cruise DeparturesRiver Cruises that depart from
North America:
United States:
Missouri: St Louis
River Cruises that visit St LouisSee all Cruises that depart from St LouisMississippi River CruisesClick on a cruise ship itinerary sailing from St Louis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just St Louis), please visit:
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14 Night - Grand Ohio River Cruise from St. Louis, MO to Pittsburgh, PAStarting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Evansville, IN; Louisville, KY; Cincinnati, OH; Maysville, KY; Marietta, OH; Pittsburgh, PA
2024 Sails: Jul 13, Aug 10,
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7 Night - Upper Mississippi River Cruise from St. Louis, MO to St. Paul, MNStarting in St. Louis, MO; with stops in Alton, IL; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2024 Sails: Jul 27,
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8 Night - St. Louis to NashvilleStarting in St. Louis, MO; with stops in Alton, IL; St. Louis, MO; Chester, IL; Cape Girardeau, MO; Paducah, KY; Dover, TN; Clarksville, TN
2024 Sails: Aug 3,
More...8 Night - St. Louis to MemphisStarting in St. Louis, MO; with stops in Alton, IL; Chester, IL; Cape Girardeau, MO; Paducah, KY; New Madrid, MO; Ashport Landing, TN; Memphis, TN
2024 Sails: Aug 31,
More... 10 Night - Mississippi River Gateway Cruise from St. Louis, MO to New Orleans, LAStarting in St. Louis, MO; with stops in Paducah, KY; New Madrid, MO; Memphis, TN; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; New Orleans, LA
2024 Sails: Sep 7,
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St Louis River Cruise Departures
