San Francisco Cruise Departures

Cruises that depart from North America: United States: California: San Francisco

Cruises that visit San Francisco

See all River Cruises that depart from San Francisco

Click on a cruise ship itinerary sailing from San Francisco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Francisco), please visit: Cruise Search or try our Virtual Cruise Advisor™.

15 Night - Hawaiian Islands - San Francisco to San Francisco aboard Royal Princess
Starting in San Francisco with stops in Lahaina, Kona, Honolulu, Ensenada
2023 Sails: Mar 12, More...

Princess Cruises, Royal Princess

15 Night - Hawaiian Islands - San Francisco to San Francisco aboard Royal Princess
Starting in San Francisco with stops in Kona, Honolulu, Lahaina, Ensenada
2023 Sails: Mar 27, More...

Princess Cruises, Royal Princess

5 Night - Comedy Themed West Coast Getaway With San Diego - San Francisco to San Francisco aboard Royal Princess
Starting in San Francisco with stops in San Diego, Ensenada
2023 Sails: Apr 11, More...

Princess Cruises, Royal Princess

7 Night - Classic California Coast - San Francisco to San Francisco aboard Royal Princess
Starting in San Francisco with stops in Santa Barbara, Los Angeles, San Diego, Ensenada
2023 Sails: Apr 16, More...

Princess Cruises, Royal Princess

7 Night - Pacific Northwest Coast - San Francisco to San Francisco aboard Royal Princess
Starting in San Francisco with stops in Astoria, Seattle, Vancouver, Victoria
2023 Sails: Apr 23, More...

Princess Cruises, Grand Princess

3 Night - Pacific Coastal - San Francisco to Vancouver aboard Grand Princess
Starting in San Francisco with stops in Victoria, Vancouver
2023 Sails: Apr 28, More...

Princess Cruises, Royal Princess

3 Night - Pacific Coastal - San Francisco to Vancouver aboard Royal Princess
Starting in San Francisco with stops in Victoria, Vancouver
2023 Sails: Apr 30, More...

Princess Cruises, Ruby Princess

7 Night - Pacific Northwest Coast - San Francisco to San Francisco aboard Ruby Princess
Starting in San Francisco with stops in Astoria, Seattle, Vancouver, Victoria
2023 Sails: Apr 30, More...

Princess Cruises, Ruby Princess

10 Night - Inside Passage (With Gb, Rt San Francisco) - San Francisco to San Francisco aboard Ruby Princess
Starting in San Francisco with stops in Juneau, Skagway, Glacier Bay National Park - Scenic Cruising, Ketchikan, Victoria
2023 Sails: May 7, More...

Carnival Cruise Lines, Carnival Miracle

4 Night - Baja Mexico From San Francisco, CA
Starting in San Francisco with stops in Ensenada
2023 Sails: May 11, 2024: May 9, More...

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San Francisco Cruise Departures