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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.

San Diego
Shore Excursions

Holland America Line (HAL), HAL Zaandam
HAL Zaandam Cruise Ship10 Night - Mexico & Sea Of Cortez
Starting in San Diego with stops in Cabo San Lucas, Loreto, Pichilingue, Mazatlan, Puerto Vallarta
2023 Sails: Mar 25, More...
Norwegian Cruise Line (NCL), NCL Norwegian Jewel
NCL Norwegian Jewel Cruise Ship7 Night - Cruise to Mexican Riviera: Cabo & Puerto Vallarta from San Diego, California
Starting in San Diego with stops in Cabo San Lucas, Puerto Vallarta, Mazatlan, Ensenada
2023 Sails: Apr 2, Apr 9, Apr 16, More...
Holland America Line (HAL), HAL Zaandam
HAL Zaandam Cruise Ship14 Night - Panama Canal
Starting in San Diego with stops in Puerto Vallarta, Huatulco, Puerto Quetzal, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena, Fort Lauderdale
2023 Sails: Apr 4, More...
Disney Cruise Line, Disney Wonder
Disney Wonder Cruise Ship4 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; San Diego, California
2023 Sails: Apr 12, Apr 16, Apr 30, May 7, More...
Norwegian Cruise Line (NCL), NCL Norwegian Jewel
NCL Norwegian Jewel Cruise Ship8 Night - Cruise to Pacific Coast: Seattle & Ketchikan to Vancouver from San Diego, California
Starting in San Diego with stops in Santa Barbara, Astoria, Seattle, Ketchikan, Vancouver
2023 Sails: Apr 23, More...
Holland America Line (HAL), HAL Eurodam
HAL Eurodam Cruise Ship4 Night - Pacific Coastal Cruise
Starting in San Diego with stops in Victoria, Vancouver
2023 Sails: Apr 24, More...
Holland America Line (HAL), HAL Nieuw Amsterdam
HAL Nieuw Amsterdam Cruise Ship4 Night - Pacific Coastal Cruise
Starting in San Diego with stops in Victoria, Vancouver
2023 Sails: Apr 26, More...
Holland America Line (HAL), HAL Volendam
HAL Volendam Cruise Ship4 Night - Pacific Coastal Cruise
Starting in San Diego with stops in Victoria, Vancouver
2023 Sails: May 2, More...
Scenic, Scenic Eclipse
Scenic Eclipse Cruises9 Night - Iconic West Coast Experience: San Diego to Vancouver aboard Scenic Eclipse (Combo)
Starting in San Diego with stops in Santa Barbara, Monterrey, San Francisco, Eureka, Astoria, Seattle, Victoria, Vancouver
2023 Sails: May 3, More...
Hurtigruten, MS Roald Amundsen
MS Roald Amundsen Cruises7 Night - U.S. West Coast - Highlights and National Parks of the Pacific from San Diego to Vancouver
Starting in San Diego, U.S.; with stops in Santa Barbara, U.S.; Redwood National Park; San Juan Archipelago; Olympic National Park, U.S.; Vancouver, Canada
2023 Sails: May 8, More...


San Diego Cruise Departures

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