Louisville River Cruises

River Cruises that visit North America: United States: Kentucky: Louisville

River Cruises that depart from Louisville

See all Cruises that visit Louisville

Ohio River Cruises

Click on a cruise ship itinerary that visits Louisville (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisville), please visit: Cruise Search or try our Virtual Cruise Advisor™.

8 Night - Louisville to Cincinnati
Starting in Louisville, KY; with stops in Madison, IN; Brandenburg, KY; Louisville, KY; Augusta, KY; Cincinnati, OH
2023 Sails: May 1, More...

American Queen Voyages, American Countess

8 Night - Kentucky Derby Cruise from Louisville to Cincinnati
Starting in Louisville, KY; with stops in Madison, IN; Brandenburg, KY; Louisville, KY; Augusta, KY; Cincinnati, OH
2023 Sails: May 1, More...

American Queen Voyages, American Countess

8 Night - Cincinnati to Nashville
Starting in Cincinnati, OH; with stops in Madison, IN; Louisville, KY; Brandenburg, KY; Henderson, KY; Paducah, KY; Dover, TN; Clarksville, TN
2023 Sails: May 8, More...

American Queen Voyages, American Countess

8 Night - Burbon: An American Spirit Cruise from Cincinnati to Nashville
Starting in Cincinnati, OH; with stops in Madison, IN; Louisville, KY; Brandenburg, KY; Henderson, KY; Paducah, KY; Dover, TN; Clarksville, TN
2023 Sails: May 8, More...

American Queen Voyages, American Countess

8 Night - Louisville to Pittsburgh
Starting in Louisville, KY; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Pittsburgh, PA
2023 Sails: May 22, Jun 5, Aug 7, 2024: Jun 15, Jun 29, More...

American Queen Voyages, American Countess

8 Night - Founder's Cruise from Louisville to Pittsburgh
Starting in Louisville, KY; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Pittsburgh, PA
2023 Sails: Jun 5, More...

American Queen Voyages, American Countess

8 Night - Louisville to Nashville
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Dover, TN; Clarksville, TN
2023 Sails: Jun 19, More...

American Cruise Lines, American Heritage

10 Night - Ohio River Cruise from St. Louis to Pittsburgh, PA
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Cincinnati, OH; Maysville, KY; Marietta, OH; Pittsburgh, PA
2023 Sails: Jul 11, Jul 31, Aug 20, Sep 9, More...

American Cruise Lines, American Heritage

10 Night - Ohio River Cruise from Pittsburgh, PA to St. Louis
Starting in Pittsburgh, PA; with stops in Marietta, OH; Maysville, KY; Cincinnati, OH; Louisville, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2023 Sails: Jul 21, Aug 10, Aug 30, Sep 19, More...

American Queen Voyages, American Countess

22 Night - Minneapolis to Pittsburgh
Starting in Minneapolis (Red Wing), MN; with stops in Red Wing, MN; Minneapolis, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Chester, IL; Cape Girardeau, MO; Paducah, KY; Henderson, KY; Owensboro, KY; Brandenburg, KY; Louisville, KY; Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Wheeling, WV; Pittsburgh, PA
2023 Sails: Jul 24, More...

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